The 'Hormone Adiponectin' is a protein hormone secreted exclusively by adipose (fat) tissue. Unlike most other adipokines, its levels are inversely related to body fat. Its primary functions include:
A. Inhibiting glucose uptake
B. Stimulating appetite
C. Promoting insulin resistance and inflammation
D. Enhancing insulin sensitivity, promoting fatty acid oxidation, and having anti-inflammatory effects
Answer: Option D
Solution (By JKExamLibrary)
Adiponectin is an abundant protein hormone secreted by adipose tissue. Uniquely, its plasma levels are inversely correlated with body fat percentage; obese individuals have lower levels. Its primary functions are highly beneficial for metabolic health: it enhances insulin sensitivity in the liver and muscles, promotes the oxidation of fatty acids (reducing fat accumulation), inhibits glucose production by the liver, and has potent anti-inflammatory and anti-atherogenic effects on the blood vessels. Low levels of adiponectin are associated with insulin resistance, type 2 diabetes, and cardiovascular disease.
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