The 'Philadelphia chromosome', associated with Chronic Myelogenous Leukemia (CML), is the result of a reciprocal translocation between chromosomes: MCQ with Answer and Explanation

The 'Philadelphia chromosome', associated with Chronic Myelogenous Leukemia (CML), is the result of a reciprocal translocation between chromosomes:
A. 8 and 14
B. 9 and 22
C. 14 and 21
D. 11 and 14
Answer: Option B
Solution (By JKExamLibrary)
The Philadelphia chromosome is a specific genetic abnormality found in the bone marrow cells of most patients with Chronic Myelogenous Leukemia (CML). It is formed by a reciprocal translocation between the long arms of chromosome 9 and chromosome 22, denoted as t(9;22). This translocation fuses the BCR gene on chromosome 22 with the ABL1 gene on chromosome 9, creating a mutant BCR-ABL1 fusion protein with constitutive tyrosine kinase activity, driving uncontrolled cell division.

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Consider statements about human nutrition: 1. Essential amino acids cannot be synthesized by the body. 2. Saturated fats are liquid at room temperature. 3. Dietary fiber aids in digestion. Which are correct?
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Correct Answer: Option A


Explanation:
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D. Cross-pollination

Correct Answer: Option C


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Self-pollination (autogamy) occurs within the same flower. Geitonogamy is pollination between different flowers of the same plant, functionally cross-pollination. Xenogamy is between different plants. Self-pollination leads to genetic uniformity.

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Identify the INCORRECT statement about bacteria:
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Correct Answer: Option A


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