Which enzyme is responsible for unwinding the DNA double helix during replication? MCQ with Answer and Explanation

Which enzyme is responsible for unwinding the DNA double helix during replication?
A. Helicase
B. DNA polymerase
C. Primase
D. Ligase
Answer: Option A
Solution (By JKExamLibrary)
Helicase unwinds the DNA helix at the replication fork by breaking hydrogen bonds between base pairs. DNA polymerase adds nucleotides, ligase seals Okazaki fragments, primase synthesizes RNA primer. This coordinated action ensures accurate semi-conservative replication. Without helicase, the strands would not separate. Energy for unwinding comes from ATP hydrolysis.

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Practice More Biology Questions

Question #1
Which branch of biology deals with the study of external form and structure of organisms?
A. Physiology
B. Morphology
C. Anatomy
D. Histology

Correct Answer: Option B


Explanation:
Morphology is the study of the form and external structure of organisms. Anatomy deals with internal structures, physiology with functions, and histology with tissues. Morphology includes aspects like shape, size, color, and pattern.

This question belongs to: Science Biology
Question #2
Which of the following is a correct statement about a typical bacterium?
A. It has a nuclear membrane.
B. It contains mitochondria.
C. It has linear chromosomes.
D. Its DNA is circular and located in the nucleoid.

Correct Answer: Option D


Explanation:
Bacteria are prokaryotes with a single circular chromosome in a nucleoid region, without a nuclear membrane. They lack membrane-bound organelles like mitochondria. Their chromosomes are not linear; eukaryotes have linear chromosomes.

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Question #3
Consider statements about human diseases: 1. Ascariasis is caused by a roundworm. 2. Ringworm is caused by a fungus. 3. Amoebiasis is caused by a bacterium. Which are correct?
A. 2 and 3 only
B. 1, 2 and 3
C. 1 and 3 only
D. 1 and 2 only

Correct Answer: Option D


Explanation:
Ascariasis is a helminthic infection caused by the intestinal roundworm Ascaris lumbricoides. Ringworm (dermatophytosis) is a superficial fungal infection of the skin, hair, or nails caused by dermatophytes like Microsporum. Amoebiasis is an intestinal infection caused by the protozoan parasite Entamoeba histolytica, not a bacterium. Thus, statements 1 and 2 are correct.

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