In genetics, the 'TATA box' is a conserved DNA sequence found in the promoter region of many eukaryotic genes. It is recognized and bound by: MCQ with Answer and Explanation

In genetics, the 'TATA box' is a conserved DNA sequence found in the promoter region of many eukaryotic genes. It is recognized and bound by:
A. DNA ligase
B. RNA polymerase I
C. TATA-binding protein (TBP), a subunit of TFIID
D. The ribosome
Answer: Option C
Solution (By JKExamLibrary)
The TATA box (consensus sequence TATAAA) is a highly conserved DNA sequence located about 25-30 base pairs upstream of the transcription start site in the promoter region of many eukaryotic genes transcribed by RNA polymerase II. It is specifically recognized and bound by the TATA-binding protein (TBP), which is a crucial subunit of the general transcription factor TFIID. The binding of TBP initiates the assembly of the pre-initiation complex, including RNA polymerase II, allowing transcription to begin.

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