In the nephron, the 'Loop of Henle' is primarily responsible for:

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The Loop of Henle is a U-shaped tube extending into the renal medulla. Its primary function is to concentrate the urine by creating a hyperosmotic gradient in the medullary interstitium through the counter-current multiplier mechanism. The descending limb is permeable to water but not salts, while the ascending limb is impermeable to water but actively transports salts out. This gradient allows the collecting duct to reabsorb water under the influence of ADH.

In the nephron, the 'Loop of Henle' is primarily responsible for: MCQ with Answer and Explanation

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