The 'Hormone Resistin' is secreted primarily by adipose tissue in humans (and by macrophages in rodents). Its primary function is to: MCQ with Answer and Explanation

Resistin is a cysteine-rich peptide hormone secreted primarily by adipose tissue in humans (though in rodents, it is mainly secreted by macrophages). Its name is derived from its proposed role in 'resistance' to insulin. Its primary function is to antagonize the action of insulin, thereby promoting insulin resistance. It does this by increasing hepatic glucose production (gluconeogenesis) and impairing glucose uptake by muscle and adipose tissue. Elevated levels of resistin are associated with obesity and type 2 diabetes, linking adiposity to insulin resistance.