The discovery of the enzyme 'restriction endonuclease' was a milestone in biotechnology. The first such enzyme was isolated by: MCQ with Answer and Explanation
The discovery of the enzyme 'restriction endonuclease' was a milestone in biotechnology. The first such enzyme was isolated by:
A. Hamilton O. Smith, Kent W. Wilcox, and Thomas J. Kelly
B. Kary Mullis
C. Watson and Crick
D. Paul Berg
Answer: Option A
Solution (By JKExamLibrary)
While restriction enzymes were first observed by Linn and Arber, the first Type II restriction endonuclease (HindII), which is the type used in genetic engineering because it cuts at specific recognition sites, was isolated and characterized by Hamilton O. Smith, Kent W. Wilcox, and Thomas J. Kelly in 1970 from Haemophilus influenzae. For this discovery, Smith shared the Nobel Prize in Physiology or Medicine in 1978. Kary Mullis invented PCR.
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Explanation:
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