The disease 'pellagra' is caused by the deficiency of: MCQ with Answer and Explanation

The disease 'pellagra' is caused by the deficiency of:
A. Vitamin B₁ (Thiamine)
B. Vitamin B₆ (Pyridoxine)
C. Vitamin B₂ (Riboflavin)
D. Vitamin B₃ (Niacin)
Answer: Option D
Solution (By JKExamLibrary)
Pellagra, characterized by dermatitis, diarrhea, and dementia (3 Ds), is caused by a deficiency of niacin (vitamin B₃) or its precursor tryptophan. It is common in populations with corn-based diets lacking tryptophan. Beriberi is due to B₁ deficiency, cheilosis to B₂, peripheral neuropathy to B₆. Niacin is a component of coenzymes NAD and NADP.

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Practice More Biology Questions

Question #1
Consider statements about the nucleus: 1. It is bounded by a single membrane. 2. It contains the nucleolus. 3. Nuclear pores allow RNA export. Which are correct?
A. 1 and 2 only
B. 1, 2 and 3
C. 2 and 3 only
D. 1 and 3 only

Correct Answer: Option C


Explanation:
The nucleus is bounded by a double membrane called the nuclear envelope, not a single membrane. It houses the nucleolus, which is the site of ribosomal RNA synthesis. The nuclear envelope is perforated by nuclear pores that regulate the bidirectional transport of molecules, including the export of mRNA to the cytoplasm. Thus, statements 2 and 3 are correct.

This question belongs to: Science Biology
Question #2
In genetics, the 'Poly-A tail' is a sequence of adenine nucleotides added to the 3' end of eukaryotic mRNA. Its primary functions include:
A. Initiating translation
B. Protecting the mRNA from degradation by exonucleases and facilitating its export from the nucleus and translation
C. Splicing out introns
D. Binding to the DNA template

Correct Answer: Option B


Explanation:
The poly-A tail is a long chain of adenine nucleotides (typically 100-250) added to the 3' end of a pre-mRNA molecule during post-transcriptional processing in the nucleus. Its primary functions are to protect the mRNA molecule from enzymatic degradation in the cytoplasm (by exonucleases), to facilitate the export of the mature mRNA from the nucleus to the cytoplasm, and to promote translation by helping to recruit ribosomes. It also plays a role in determining the lifespan of the mRNA in the cytoplasm.

This question belongs to: Science Biology
Question #3
In the five-kingdom classification, which kingdom includes organisms that are eukaryotic, multicellular, and obtain nutrition by absorption?
A. Plantae
B. Monera
C. Fungi
D. Protista

Correct Answer: Option C


Explanation:
Fungi are eukaryotic, mostly multicellular (except yeast), and are heterotrophic by absorption (saprophytic or parasitic). Their cell walls contain chitin. Monera are prokaryotic, Protista are unicellular eukaryotes, Plantae are autotrophic multicellular organisms. Fungi play key roles as decomposers in ecosystems.

This question belongs to: Science Biology