The 'Hormone Adrenocorticotropic Hormone' (ACTH) is secreted by the anterior pituitary. Its primary target and function are: MCQ with Answer and Explanation

The 'Hormone Adrenocorticotropic Hormone' (ACTH) is secreted by the anterior pituitary. Its primary target and function are:
A. The thyroid gland; stimulating thyroid hormone release
B. The adrenal medulla; stimulating adrenaline release
C. The gonads; stimulating sex hormone production
D. The adrenal cortex; stimulating the production and release of glucocorticoids (primarily cortisol)
Answer: Option D
Solution (By JKExamLibrary)
Adrenocorticotropic Hormone (ACTH) is a peptide hormone secreted by the corticotroph cells of the anterior pituitary gland. Its primary target is the adrenal cortex (the outer layer of the adrenal glands). ACTH stimulates the growth of the adrenal cortex and the synthesis and secretion of its steroid hormones, primarily the glucocorticoids (like cortisol), and to a lesser extent, androgens and mineralocorticoids. ACTH secretion is controlled by Corticotropin-Releasing Hormone (CRH) from the hypothalamus and by the negative feedback of cortisol.

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