The 'Hormone Gastric Inhibitory Peptide' (GIP), also known as Glucose-dependent Insulinotropic Peptide, is secreted by the K cells of the duodenum and jejunum. Its primary function in the presence of elevated blood glucose is to: MCQ with Answer and Explanation

The 'Hormone Gastric Inhibitory Peptide' (GIP), also known as Glucose-dependent Insulinotropic Peptide, is secreted by the K cells of the duodenum and jejunum. Its primary function in the presence of elevated blood glucose is to:
A. Stimulate gastric acid secretion
B. Inhibit insulin release
C. Stimulate glucagon release
D. Inhibit gastric acid secretion and stimulate insulin release from the pancreas
Answer: Option D
Solution (By JKExamLibrary)
Gastric Inhibitory Peptide (GIP), now more commonly called Glucose-dependent Insulinotropic Peptide, is an incretin hormone secreted by the K cells of the small intestine in response to the ingestion of food, particularly glucose and fats. Its name reflects its two main actions: 1) It inhibits gastric acid secretion and slows gastric emptying (the 'gastric inhibitory' effect). 2) In the presence of elevated blood glucose, it potently stimulates the beta cells of the pancreas to secrete insulin (the 'insulinotropic' effect), preparing the body to handle the incoming nutrients.

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