The 'Hormone Glucagon' is secreted by the alpha cells of the pancreas. Its primary effect on the liver is to: MCQ with Answer and Explanation

The 'Hormone Glucagon' is secreted by the alpha cells of the pancreas. Its primary effect on the liver is to:
A. Increase the uptake of glucose by liver cells
B. Promote the conversion of glucose to glycogen (glycogenesis)
C. Inhibit the release of glucose into the blood
D. Promote the breakdown of glycogen to glucose (glycogenolysis) and the synthesis of glucose from non-carbohydrates (gluconeogenesis)
Answer: Option D
Solution (By JKExamLibrary)
Glucagon is a peptide hormone secreted by the alpha cells of the pancreatic islets in response to low blood glucose levels (hypoglycemia). Its primary target is the liver, where it acts to raise blood glucose levels. It stimulates glycogenolysis (the breakdown of stored glycogen into glucose) and gluconeogenesis (the synthesis of new glucose from non-carbohydrate sources like amino acids and glycerol). It also promotes the breakdown of fats (lipolysis) in adipose tissue. It has the opposite effect of insulin.

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Correct Answer: Option D


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Correct Answer: Option D


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