The 'Avery, MacLeod, and McCarty' experiment in 1944 provided strong evidence that:
A. RNA is the genetic material in some viruses
B. Lipids are the genetic material
C. Proteins are the genetic material
D. DNA is the genetic material
Answer: Option D
Solution (By JKExamLibrary)
In 1944, Oswald Avery, Colin MacLeod, and Maclyn McCarty conducted a landmark experiment building on Griffith's transformation experiment. They purified various macromolecules (DNA, RNA, proteins, lipids) from the virulent S strain of Streptococcus pneumoniae and tested which one could transform the non-virulent R strain into the virulent form. They found that only DNA could cause transformation, and this activity was destroyed by DNase but not by RNase or proteases. This provided the first strong, direct evidence that DNA, not protein, is the genetic material.
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