The scientist who proposed the 'one gene-one enzyme' hypothesis was: MCQ with Answer and Explanation

The scientist who proposed the 'one gene-one enzyme' hypothesis was:
A. Watson and Crick
B. Beadle and Tatum
C. Meselson and Stahl
D. Hershey and Chase
Answer: Option B
Solution (By JKExamLibrary)
George Beadle and Edward Tatum, working with Neurospora crassa, proposed that each gene controls the synthesis of a specific enzyme (later refined to one gene-one polypeptide). Watson and Crick discovered DNA structure, Hershey-Chase confirmed DNA as genetic material, Meselson-Stahl demonstrated semi-conservative replication.

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Practice More Biology Questions

Question #1
The scientist who discovered the enzyme reverse transcriptase was:
A. James Watson
B. Howard Temin and David Baltimore
C. Kary Mullis
D. Francis Crick

Correct Answer: Option B


Explanation:
Howard Temin and David Baltimore independently discovered reverse transcriptase in retroviruses in 1970, an enzyme that synthesizes DNA from RNA. Watson and Crick DNA structure, Mullis PCR.

This question belongs to: Science Biology
Question #2
The 'Hormone Vasoactive Intestinal Peptide' (VIP) is a neuropeptide found in the central nervous system and the gut. Its primary functions in the gut include:
A. Inhibiting intestinal motility
B. Stimulating intestinal water and electrolyte secretion, relaxing intestinal smooth muscle, and stimulating pancreatic bicarbonate secretion
C. Stimulating gall bladder contraction
D. Stimulating gastric acid secretion

Correct Answer: Option B


Explanation:
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide that acts as a neurotransmitter and a hormone. In the gastrointestinal tract, its primary functions are stimulatory and relaxant: it stimulates the secretion of water and electrolytes into the intestinal lumen (acting as a secretagogue), relaxes the smooth muscle of the gut (including the lower esophageal sphincter, stomach, and gall bladder), and stimulates the pancreas to secrete a bicarbonate-rich juice. It also causes vasodilation in the gut. Excessive VIP secretion can lead to severe watery diarrhea (as in VIPoma).

This question belongs to: Science Biology
Question #3
The structure that regulates the passage of food from the stomach to the small intestine is the:
A. Pyloric sphincter
B. Ileocecal valve
C. Anal sphincter
D. Cardiac sphincter

Correct Answer: Option A


Explanation:
The pyloric sphincter is a ring of smooth muscle at the junction of the stomach and duodenum. It controls the release of chyme from the stomach into the small intestine in small amounts. The cardiac sphincter is between the esophagus and stomach, ileocecal valve between small and large intestine.

This question belongs to: Science Biology