The technique used to separate proteins based on their isoelectric point is: MCQ with Answer and Explanation

The technique used to separate proteins based on their isoelectric point is:
A. PCR
B. Isoelectric focusing
C. SDS-PAGE
D. Western blotting
Answer: Option B
Solution (By JKExamLibrary)
Isoelectric focusing (IEF) separates proteins in a pH gradient according to their isoelectric point (pI), the pH at which a protein has no net charge and stops migrating. SDS-PAGE separates by size, Western blotting detects specific proteins after separation, PCR amplifies DNA. IEF is often used in 2D gel electrophoresis.

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